All posts tagged: genetics

NYT bestselling author Bob Kolker talks about his oprah book club pick HIDDEN VALLEY ROAD, the history–and future–of schizophrenia, family trauma, resillience, & so much more

By Leslie Lindsay  A razor-sharp tale of one American family ravaged by the devastating effects of mental illness, schizophrenia, in particular. ~WRITERS INTERVIEWING WRITERS|ALWAYS WITH A BOOK~ WEDNSDAYS WITH WRITERS OPRAH’S BOOK CLUB PICK #1 NEW YORK TIMES BESTSELLER  ONE OF THE NEW YORK TIMES TOP TEN BOOKS OF THE YEAR ONE OF THE WALL STREET JOURNAL TOP TEN BOOKS OF THE YEAR PEOPLE’S #1 BEST BOOK OF THE YEAR  Named a BEST BOOK OF THE YEAR by The New York Times, The Washington Post, NPR, TIME, Slate, Smithsonian, The New York Post, and Amazon  Meet the Galvins. They are your all-American family living in Colorado in the 1950s-70s, except they have one big secret, and one big family: half of the dozen children are afflicted with mental illness. Welcome home to HIDDEN VALLEY ROAD: Inside the Mind of an American Family (Doubleday, April 2020) and meet Don and Mimi, their ten good-looking boys, and equally stunning daughters. After WWII, Don’s work with the Air Force brings them to Colorado, where the baby-making doesn’t seem to cease. But not to worry, Mimi has it all under control. She’s …

Phenom skiier, a terrible accident, murder, motherhood, mental illness, and so much more in this chilling tale of domestic suspense~JT Ellison on TEAR ME APART

By Leslie Lindsay  Dark domestic suspense meets police procedural in this unique read encompassing genetics, secrets, lies, and so much more in TEAR ME APART. Join me in conversation with J.T. as she talks about the stigma of mental illness lifting, how she’s been haunted by the book for awhile now, the fact that writer’s block is your story’s way of saying something’s not working and so much more. How far would a loving mother go to protect her superstar daughter? Mindy Wright is seventeen years old and a spectacular downhill skier in Vail, Colorado. She’s vying for a position in the U.S. Olympic team when a horrible crash sends her to the hospital with a broken leg requiring surgery. During the pre-op blood work, doctors discover she is suffering from a severe form of leukemia. Only a stem cell transplant will save her. But no one in her immediate family is a genetic match. How could that be?  Told from multiple POVs, TEAR ME APART is a very complex, multilayered read, revealing decades-old secrets and lies.  I …

Debut Novelist Julie Clark talks about science, motherhood, love, and so much more in her dazzling good read, THE ONES WE CHOOSE

By Leslie Lindsay  Shattering original and beautifully written book about secrets, science, DNA, mothers, and the trauma of our ancestors living in each and every one of us. THE ONES WE CHOOSE is such a glimmering debut by an author to watch.  You’ll read Julie Clark’s debut and think, “this woman has got to be a scientist,” but she’s not. She’s a 5th grade teacher and mother, and while those skills and traits come through in THE ONES WE CHOOSE, it’s her effortless blend of genetics that made me swoon. Geneticist Paige Robson is struggling. She’s always had everything together, until her son starts asking about his biological dad. Eight-year old Miles was conceived via sperm donor and while he knows this, he can’t help but feel disconnected. He doesn’t fit in with the other children at school, who all seem to have active, engaged fathers. Plus, Paige’s romantic life isn’t all that great (she has difficultly being open), and her father has just returned; attempting to make up for lost time. “How could I not love a debut about …

Wednesdays with Writers: Ella Joy Olsen talks about the fascination of genealogy, a tie-in from her first book; grief, hope, love, pre-pub jitters, the development of a title and so much more in her new book, WHERE THE SWEET BIRD SINGS

By Leslie Lindsay  A thoughtful and wholesome story about love, grief, hope, resilience, but also family history and genealogy. WHERE THE SWEET BIRD SINGS (Kensington, August 29 2017) is Ella Joy Olsen’s second novel, and you’ll find a lovely little twist between the two titles, though they are intended as stand-alone reads.   Emma Hazelton and her husband are at a crossroads since the death of their darling—and much wanted child, Joey—died due to a rare genetic disease. Emma’s been trying to move on, but it’s just so hard. Meanwhile, Noah is ready for them to try again for another baby. It’s been a year, but…Emma agrees to help her mother sort through her recently-deceased grandfather’s belongings and she stumbles across a perplexing 1916 wedding photograph. WHERE THE SWEET BIRD SINGS is told entirely in Emma’s POV, whereas Olsen’s first book, ROOT PETAL THORN was told by multiple narrators. WHERE THE SWEET BIRD SINGS is about family, deeply hidden and buried secrets, hope, and the interesting marriage of family history/ancestry with genealogy. I found the story–and mystery–richly …

Fiction Friday: Excerpt from Slippery Slope

By Leslie Lindsay Combing back through that novel-in-progress–trimming, saving, adding–general revising.  Here’s one of the early chapters.  [Remember, this is a work of original fiction and is not intended to represent anyone living or dead.  It it a figment of the author’s imagination.  Borrowing or making your own is strictly prohibited.  Thanks for your understanding].  Enjoy! An excepert from Slippery Slope: “I married Joe for several reasons.  One, he asked me.  Two, he had good genes.  And perhaps three, I was in love.  With a mass of coiled PhD brains in his head, I knew he’d pass on intelligence, a trait 86% of the population finds valuable, along with a sense of humor, creativity, and problem-solving ability.  And so we made babies.  Two of them to be exact, at the preferred two-and-a-half year interval, enough time physicians believe a woman’s body has healed and returned to normal, and psychologists have determined is the “appropriate developmental spacing.”  But now I wonder, would Kenna and Madi’s sweet chatter somehow sound differently if they had been conceived with Steve, …

Apraxia Monday: Chapter 6 Excerpt

By Leslie Lindsay An excerpt from “Speaking of Apraxia:  A Parent’s Guide to Childhood Apraxia of Speech” (Woodbine House, March 2012). 6 So What Caused All of This? Theories and Medical Diagnoses Related to CAS You’d like to blame someone, anyone, for the misfortunate combination of luck and biology that lead to your child having Childhood Apraxia of Speech. But chances are, there is nothing or no one who can take the blame. There is a lot of conflicting information out there about what causes CAS. To date, the professionals can’t agree on a cause—but there are lots of theories. I am certainly no expert in CAS theory, so if you really have an interest in this topic, I urge you to seek out additional resources. The Nuts and Bolts of This Chapter A review of the ASHA 2007 Ad Hoc Technical Document on Childhood Apraxia of Speech, which summarized what is known about CAS and advanced three theories about is causes. . Familial factors, infectious diseases, and medically based diagnoses that may involved with …